Cordyceps in the fight against arthritis:

Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes progressive joint destruction. It is characterized by synovial hyperplasia and cartilage destruction.

Hyperplasia of the synovial membrane is a pathological growth of the inner membrane of the joint, which is called the synovial membrane. Normally, this membrane is thin, but in rheumatoid arthritis it thickens significantly due to inflammation and increased proliferation (reproduction) of cells.

Cartilage destruction is the destruction of cartilage tissue that covers the articular surfaces of bones.
However, a recent study by scientists from South Korea showed that the substance cordycepin, isolated from the mushroom Cordyceps militaris (Cordyceps militaris), could become a potential remedy for the prevention of inflammation in rheumatoid arthritis.

The study was conducted on synovial fibroblasts isolated from the tissues of 12 patients with rheumatoid arthritis. These cells play a key role in the development of inflammation and joint destruction in rheumatoid arthritis.

The results showed that
"cordycepin inhibited IL-1β-induced expression of MMP-1 and MMP-3 in synovial fibroblasts in rheumatoid arthritis (RA) in a dose-dependent manner." MMP-1 and MMP-3 are enzymes that destroy joint cartilage. Their inhibition can prevent progression

In addition, cordycepin
"specifically blocked IL-1β-induced ENA-78 production in the SFRA." ENA-78 is a pro-inflammatory chemokine that attracts immune cells to joints, increasing inflammation. Its inhibition may also have an anti-inflammatory effect.

It is important to note that
"treatment of synovial fibroblasts with cordycepin (50 μM or 100 μM) for 24 hours did not cause any significant changes in cell viability." That is, at the indicated concentrations, cordycepin did not show toxicity to cells.

Based on these results, the authors of the study concluded that
"cordycepin may be a potential candidate for the prevention of inflammation in rheumatoid arthritis".

Cordycepin, a bioactive substance from the mushroom Cordyceps militaris, has demonstrated anti-inflammatory properties and a significant ability to prevent the destruction of cartilage tissue in joints. In addition, the use of the mushroom was found to be safe and non-toxic to humans.

You can also buy them in our store.
1. Cordyceps fruit
2. Cordyceps capsules
3. Cordyceps extract
4. Forest Cardio Power

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