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Effects of Cordyceps on reproductive function in men with diabetes
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Effects of Cordyceps on reproductive function in men with diabetes

Diabetes mellitus (DM) is a metabolic disorder characterized by a chronic increase in the level of sugar (glucose) in the blood above the norm. The number of patients with DM is growing rapidly both among children and among adults. DM increases the risk of developing other related complications,

DM is often associated with sexual dysfunction in men and women.DM negatively affects male reproductive capacity in both humans and animals. Male patients with DM often have sexual dysfunctions, such as decreased libido and impotence, disruption of the sperm production process, which leads to a decrease in sperm motility, concentration and viability, erectile and ejaculation problems, decreased serum testosterone and antioxidant levels, which can even lead to infertility.

Conducted research

Between July 2018 and September 2019, a group of scientists from Thailand conducted a study on the aphrodisiac properties of Cordyceps militaris in male diabetic rats. This study aimed to study the effect of Cordyceps militaris on reproductive function in male diabetic rats and to understand the mechanism of action of Cordyceps

Research methods

Scientists induced diabetes in animals by injecting them with a special substance. After 3 days, the blood glucose level was determined using a glucometer. Rats with high blood glucose levels were considered diabetic and were used in this experiment. The animals were divided into 4 groups: Group 1 consisted of healthy who were injected with Tween (a substance that helps mix other substances together); Group 2 consisted of healthy rats receiving 100 mg/kg Cordyceps militaris; Group 3 consisted of diabetic rats that received a 1% suspension of Tween (a substance that helps mix other substances together); and group 4 consisted of diabetic rats treated with 100 mg/kg Cordyceps militaris. The blood glucose level and body weight of the rats in all groups were monitored once a week during the experiment.

During the research, tests were conducted on sexual behavior, sperm concentration, their appearance and structure, after which the percentage of viability and deviations from the norm were determined. The level of testosterone in the blood serum and the parameters of the antioxidant system, which helps to determine how effectively the body's defense system works, were also determined.

The results

A study of the aphrodisiac properties of Cordyceps militaris in male diabetic rats revealed significant positive effects on reproductive function. The diabetic rat group treated with Cordyceps (100 mg/kg) showed significant improvement compared to the diabetic group (without treatment) in the following parameters

Serum testosterone level increased by 308.3%

Sperm count increased by 89%

Sperm motility increased by 18.2%

Sperm viability improved by 10%

MDA (Reduction of Oxidative Stress) has an effect on improving the general state of health and reducing the risk of developing chronic diseases. The improvement was observed by 29.73%.

GSH (Enhancing Antioxidant Defense) helps protect cells from damage caused by free radicals and slows down the aging process. Improvement was seen by 62.8%.

CAT (Improved Detoxification) helps the body remove harmful substances. The improvement was observed by 18.19%.

In general, sexual desire increased and the time required to initiate intercourse decreased, sexual stamina and overall sexual function improved.

Conclusion

These results confirm that Cordyceps militaris has potential antidiabetic and aphrodisiac properties that may contribute to the improvement of reproductive function in male diabetic rats. According to this study, the use of Cordyceps militaris may be beneficial in reducing the reproductive impairment caused by diabetes. due to its antioxidant properties and ability to increase testosterone levels, and increased serum testosterone levels after Cordyceps militaris treatment may be responsible for improved sexual behavior and increased libido, reduces oxidative stress in testicular dysfunction, and may improve sperm concentration, motility, and viability.

Interestingly, Cordyceps militaris stimulated sexual behavior not only in diabetic patients, but also in healthy subjects. The study showed that serum testosterone and estrogen levels significantly increased 2 and 6 weeks after taking Cordyceps militaris, which also indicates a high preventive effect.

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1. Cordyceps fruit
2. Cordyceps capsules
3. Cordyceps extract
4. Forest Cardio Power



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